Lizzo to Rebel Wilson: 11 Hollywood celebrities who have used Ozempic for weight loss

Is Ozempic for weight reduction useful? A  host of Hollywood celebrities have admitted to utilizing Ozempic, which has change into extensively standard amongst individuals who need to drop pounds. It is among the manufacturers with semaglutide because the energetic ingredient to handle sort 2 diabetes. Though the US Meals and Drug Administration has permitted this treatment solely to handle blood sugar ranges in individuals with sort 2 diabetes, the injectable treatment has gained reputation as a weight reduction drug. It’s not simply influencers and actuality TV stars who’ve experimented with it. Hollywood celebrities like Amy Schumer and Insurgent Wilson have additionally admitted to utilizing it to drop pounds. However not everybody has had a constructive expertise

Listed here are a number of the Hollywood celebrities who’ve admitted to utilizing Ozempic for weight reduction, and what they mentioned about its advantages or uncomfortable side effects.

1. Lizzo

Singer and rapper Lizzo is the most recent superstar to open up about utilizing the a lot talked-about weight reduction drug. Whereas discussing her weight reduction efforts, she revealed on the Simply Trish podcast in June 2025 that she had tried Ozempic. “It’s simply the science for me, energy in versus energy out. Ozempic works since you eat much less meals.” Explaining the way it works, she mentioned, “It makes you’re feeling full, so in case you can simply try this by yourself and get thoughts over matter.”

2. Kathy Bates

Final 12 months, Oscar-winning actress Kathy Bates mentioned that she misplaced 80 kilos over the previous seven years by making life-style modifications. She then misplaced one other 20 kilos by taking Ozempic. “There’s been a whole lot of discuss that I simply was in a position to do that due to Ozempic. However I’ve to impress upon individuals on the market that this was laborious work for me, particularly through the pandemic. It’s very laborious to say you’ve had sufficient,” she informed Individuals.

3. James Corden

Comic-actor-TV host James Corden mentioned that he tried Ozempic, but it surely was not very efficient for him. “I attempted Ozempic, and it gained’t be shocking to you once you take a look at me now, that it didn’t actually work,” Corden mentioned in one of many episodes of his podcast, This Lifetime of Mine with James Corden, in 2024. “I attempted it for a bit after which what I realised was I used to be like, ‘Oh no, nothing about my consuming has something to do with being hungry.’ All this does is make you’re feeling not hungry.”

4. Amy Schumer

Actress and comic Amy Schumer received sick after taking the load loss drug. “I’ve this gene, GDF 15, which makes you extraordinarily liable to nausea, which is why I used to be so sick throughout my being pregnant,” Schumer, who gave beginning to her son Gene in 2019, mentioned throughout The Howard Stern Present in January 2025. “So I attempted Ozempic virtually 3 years in the past, and I used to be like bedridden. I used to be vomiting. After which you haven’t any vitality.” She “misplaced 30 kilos so fast” and “regarded nice” after taking Ozempic, however she couldn’t raise her “head off the pillow, so what’s the purpose?”

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5. Sharon Osbourne

TV persona Sharon Osbourne can also be one of many celebrities who used Ozempic to assist handle her weight. “I misplaced 42 kilos now and it’s simply sufficient,” she mentioned throughout an episode of Piers Morgan’s podcast Piers Morgan Uncensored in 2023. “I didn’t really need to go this skinny, but it surely simply occurred and I’ll in all probability put all of it on once more quickly.”

Speaking in regards to the uncomfortable side effects of Ozempic, she mentioned, “At first, I imply, you’re feeling nauseous. You don’t throw up bodily however you’ve received that feeling. I used to be about two, three weeks the place I felt nauseous the entire time. You get very thirsty and also you don’t need to eat. That’s it.” She doesn’t need kids to get hooked to it. “You’ve received to maintain these things away from youthful individuals as a result of they are going to go berserk on it, and it’s not proper,” she mentioned.

6. Insurgent Wilson

Actress Insurgent Wilson admitted to utilizing Ozempic for a while. “Somebody like me might have a bottomless urge for food for sweets, so I believe these medicine could be good,” she mentioned throughout an interview with The Sunday Occasions in 2024. The Pitch Excellent actress, who not makes use of Ozempic, mentioned, “Nobody other than my mother wished me to drop pounds. Individuals thought I’d lose my pigeonhole in my profession, taking part in the fats humorous character, they usually wished me to proceed in that.”

7. Chelsea Handler

Comic Chelsea Handler talked about unknowingly being prescribed Ozempic. “So, my anti-aging physician simply fingers it out to anyone. I didn’t even know I used to be on it,” mentioned Handler throughout her look on the podcast Name Her Daddy in 2023. Her physician informed her, “Should you ever need to drop 5 kilos, that is good.”

Chandler recalled giving herself a dose of the treatment after a trip. “I got here again from a trip and I injected myself with it. I went to lunch with a girlfriend just a few days later, and he or she was like, ‘I’m not likely consuming something. I’m so nauseous, I’m on Ozempic,’” she recalled. “And I used to be like, ‘I’m sort of nauseous too.’ However I had simply come again from Spain and was jet-lagged.” Handler’s good friend requested her if she was certain she wasn’t on Ozempic. The comic mentioned that she was simply “on semaglutide.” Her good friend defined, “That’s Ozempic.”

8. Kelly Osbourne

Singer and actress Kelly Osbourne, daughter of Ozzy and Sharon Osbourne, was all reward for Ozempic. “I believe it’s superb,” she mentioned in regards to the treatment throughout an interview with E! Information final 12 months. “There are one million methods to drop pounds, why not do it via one thing that isn’t as boring as understanding?”

9. Macy Grey

Grammy winner Macy Grey is among the celebrities who didn’t have a superb expertise with Ozempic. “Oh, boy my abdomen hurts. I took Ozempic. I can’t go to the toilet, and I used to be up all night time,” she mentioned throughout an episode of The Surreal Life: Villa of Secrets and techniques in 2024. On why she determined to attempt Ozempic, she mentioned, “Quietly, I’m sort of a useless individual. I’ve gained a whole lot of weight over the previous couple years, and that is proper in regards to the time when everyone begins speaking about this Ozempic.”

10. Tori Spelling

Actress Tori Spelling revealed that she used two weight reduction medicine — Ozempic and Mounjaro. “I did Mounjaro and everybody admits it now,” she mentioned throughout her Misspelling podcast in 2024. Earlier than that, she used Ozempic when she was at 160 kilos. “I attempted Ozempic and it didn’t work for me.”

11. Stephen Fry

English actor and comic Stephen Fry mentioned that he tried Ozempic years in the past. “I’m an early adopter of this stuff,” he mentioned throughout an episode of River Café Desk 4 podcast in 2024.

“I occurred to be in America, and I’d examine it, and I requested my physician in America, my doctor as they prefer to name them, and he mentioned, ‘I believe I can get you some.’ He tried me on it, and the primary week or so, I used to be considering, ‘That is astonishing. Not solely do I not need to eat, I don’t need any alcohol of any type. That is going to be sensible.’” Then he began feeling sick. “I used to be actually throwing up 4, 5 occasions a day and I believed, ‘I can’t do that.’ In order that’s it.”

A phrase of warning

Nausea, constipation and vomiting are a number of the widespread uncomfortable side effects of Ozempic. Use this weight reduction drug solely after consulting a physician.