Mounjaro benefits and side effects explained: All you need to know

Weight problems is a significant well being concern on this planet, as thousands and thousands of individuals have extreme fats deposits of their our bodies. In 2022, 890 million folks have been discovered to be residing with weight problems, in accordance with the World Well being Group. So, it comes as no shock that pharmaceutical corporations and authorities businesses globally try to give you an answer. That has brough weight reduction medication into the image. Most of those prescribed medicines assist by mimicking the hormones that play a key position in regulating urge for food and starvation. Mounjaro is one such medicine, which is used to handle sort 2 diabetes and in addition has weight reduction advantages. Know all about the advantages and negative effects of Mounjara, a weekly injectable drug, earlier than utilizing it to shed weight.

What’s Mounjaro?

Mounjaro is the model identify for tirzepatide, a once-weekly injectable medicine accredited by the US Meals and Drug Administration for sort 2 diabetes. It is usually used off-label for weight reduction, which implies it’s prescribed for a goal aside from what it’s been accredited for.

“Not like earlier GLP-1 agonists like semaglutide, which is offered beneath completely different manufacturers, together with Ozempic, Mounjaro acts on two incretin hormones GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1),” says endocrinologist Dr Archana Juneja. This fashion, it enhances its efficacy for each glycemic management and weight reduction.

What are the advantages of Mounjaro?

Listed below are the important thing advantages of Mounjaro:

1. Manages diabetes

It helps in managing sort 2 diabetes by growing the manufacturing of insulin within the physique. This in flip helps in reducing blood sugar, as the quantity of sugar your liver produces decreases. “It stimulates the pancreas to launch extra insulin in a glucose-dependent method, which means it primarily works when blood glucose ranges are excessive, decreasing the chance of hypoglycemia,” explains the skilled.

2. Helps with weight reduction

Mounjaro has demonstrated vital weight discount in non-diabetics as nicely. A brand new examine, introduced on the European Congress on Weight problems in Spain in Might 2025, discovered {that a} weekly dose of tirzepatide can result in vital and constant weight reduction for as much as 3 years in overweight or chubby adults who should not diabetics. “This drugs works on the mind’s hypothalamus, which controls starvation. It helps to suppress urge for food and decelerate gastric emptying, resulting in early satiety and aiding weight reduction,” says the skilled.

Mounjaro doses

The doses improve steadily, however ensure that to comply with your physician’s recommendation.

• The advisable beginning dose is 2.5 mg, which must be injected beneath the pores and skin of your abdomen, thigh, or higher arm as soon as weekly, as per the FDA.
• 4 weeks later, the dose shall be elevated to five mg.
• The utmost dosage is 15 mg, which ought to be injected subcutaneously as soon as weekly.

In case you miss a dose, a jab must be given as quickly as potential inside 4 days after the missed dose.

Does Mounjaro trigger hair loss?

Hair loss is just not a recognized or frequent facet impact of Mounjaro itself. Nevertheless, speedy weight reduction, which is frequent with tirzepatide, can result in telogen effluvium, a brief hair loss downside. “Such a hair loss is normally reversible and never instantly tied to the load loss drug’s mechanism,” says Dr Juneja. In case you expertise hair loss whereas taking Mounjaro, try to be checked for dietary deficiencies like iron, zinc, vitamin B12 and protein.

What are the negative effects of Mounjaro?

Listed below are a few of the negative effects of Mounjaro:

• Nausea: It’s a frequent facet impact, skilled once you begin taking this weight reduction drug. “It’s usually as a result of delayed gastric emptying attributable to the medicine, and normally improves because the physique adjusts to the drug,” says the skilled.
• Vomiting: It happens in some folks, notably if the dose is elevated too rapidly. It’s the physique’s response to modifications in digestion and urge for food regulation.
• Diarrhea: Free or frequent stools may end up from modifications in intestine motility, which is the stretching of the muscular tissues within the gastrointestinal tract.
• Constipation: If not diarrhea, some folks might expertise slowed bowel actions or have problem passing stool on account of modifications in digestion.
• Indigestion: A sense of discomfort or burning within the higher stomach after consuming could also be felt whereas utilizing Mounjaro.
• Pancreatitis: Irritation of the pancreas is a uncommon, however severe facet impact of this weight reduction drug. It may possibly result in extreme stomach ache, nausea and vomiting.
• Hypoglycemia (low blood sugar): Mounjaro alone has a low danger of inflicting hypoglycemia. “Nevertheless, if utilized in mixture with insulin or sulfonylureas (anti-diabetic medicines), the chance will increase. Sweating, dizziness and confusion are a few of its signs,” says the skilled.
• Liver toxicity: It’s uncommon, however hepatotoxicity, also called liver toxicity, could also be related to tirzepatide use. Throughout a examine, revealed within the European Journal Of Case Stories In Inside Medication, researchers discovered that liver toxicity was skilled after escalating doses of tirzepatide.